SEQIRUS INC

ACQUISITION OF INFLUENZA A(H2NX) VIRUS VACCINE CANDIDATE(S) AND CLINICAL TRIAL

DE-OBLIGATE FUNDING TO DISPOSE OF ALL H5N8 A/GYRFALCON ON CLIN 3401B - PRIOR CONTRACTS: STORAGE AND STABILITY

THE PURPOSE OF THIS MODIFICATION IS TO: 1) EXERCISE OPTION YEAR 10 (CLIN 0009J). THE PERIOD OF PERFORMANCE FOR THIS OPTION PERIOD IS JUNE 15, 2025 THROUGH JANUARY 31, 2027. 2) AS A RESULT OF THIS CHANGE, THE TOTAL FUNDING VALUE HAS INCREASED TO

THE PURPOSE OF THIS TASK ORDER IS TO PROCURE SERVICES FOR STORAGE AND STABILITY VACCINE BULK LOTS FROM PRIOR CONTRACTS FOR DEPARTMENT OF HEALTH AND HUMAN SERVICES UNDER IDIQ CONTRACT #75A50122D00004.

THE PURPOSE OF THIS MODIFICATION IS TO UPDATE THE LANGUAGE FOR SECTION B.2(D), SECTION C.2 MILESTONES, AND SECTION H.22 LIABILITY PROTECTION. THE TOTAL FUNDING AND CONTRACT VALUE HAS NOT CHANGE. ALL OTHER TERMS AND CONDITIONS ARE IN FULL FORCE

(1) PROVIDE MEDICAL COUNTERMEASURES (MCMS), SUCH AS VACCINES AND ADJUVANTS, FOR PANDEMIC PREPAREDNESS AND RESPONSE OR AS REQUIRED IN RESPONSE TO AN HHS DESIGNATED PUBLIC HEALTH EMERGENCY; (2) PRODUCE VACCINES AGAINST INFLUENZA VIRUS, AND INFLUENZA V

CONTRACT CLOSEOUT AND DEOBLIGATE EXCESS FUNDS

TO CLOSE THIS CONTRACT IN LINE WITH FAR 4.804, TO UPDATE THE CONTRACTING OFFICER TO DEVIN FITZMAURICE, AND TO DE-OBLIGATE $57,834.53 IN EXCESS FUNDS SO THE TOTAL OBLIGATION IS NOW $36,825.00.

TO CLOSE THIS CONTRACT IN LINE WITH FAR 4.804, TO UPDATE THE CONTRACTING OFFICER TO DEVIN FITZMAURICE, AND TO DE-OBLIGATE $402,112.00 IN EXCESS FUNDS SO THE TOTAL OBLIGATION IS NOW $0.00.

DOD STORAGE OF H5N1 AND H7N9 ANTIGEN BULK LOTS AND MF59 ADJUVANT BULK LOTS UNDER CONTRACT HHSO100201200014I

THE PURPOSE OF THIS MODIFICATION IS INCORPORATE CHANGES AND ADD FUNDS FOR FULL INVESTMENT INTO THE VMI.

THE PURPOSE OF THIS TASK ORDER IS TO PERFORM A SHORT-TERM PHYSICAL AND CHEMICAL COMPATIBILITY (PC) STUDY ON THE ANTIGEN AND MF59 DOSING COMBINATIONS TO SUPPORT OF THE INTENDED HOLD TIME FOR THE BARDA SPONSORED BPI-23-001 STUDY.

THE PURPOSE OF THIS MODIFICATION IS TO REFLECT THE FOLLOWING: 1. INCREASE THE QUANTITIES OF CLIN 0007C AND CLIN 1007C IN OPTION 1 FOR STORAGE AND STABILITY. 2. UPDATE STATEMENT OF WORK TO REFLECT CHANGE IN QUANTITIES. 3. PROVIDE FUNDING AND EXERCI

THE PURPOSE OF THIS MODIFICATION IS TO EXERCISE CLIN 022 AND PURCHASE ADDITIONAL LOTS UNDER CLIN 017.

THE PURPOSE OF THIS MODIFICATION IS TO REFLECT THE FOLLOWING: 1. UPDATE THE STATEMENT OF WORK FOR OPTION 4. 2. EXERCISE AND FUND OPTION 4 WITH A QUANTITY OF 3.45M DOSES, AND A PERIOD OF PERFORMANCE FROM AUGUST 20, 2024 - MAY 9, 2025. 3. PROVIDE FU

TO CLOSE THIS CONTRACT IN LINE WITH FAR 4.804, TO UPDATE THE CONTRACTING OFFICER TO DEVIN FITZMAURICE, AND TO DE-OBLIGATE $8,625.46 IN EXCESS FUNDS SO THE TOTAL OBLIGATION IS NOW $4,705.52.

THE PURPOSE OF THIS MODIFICATION IS TO EXERCISE OPTION YEAR 09 (0009I).

STORAGE AND STABILITY OF ANTIGEN AND ADJUVANT BULK LOTS AND FINAL CONTAINERS

THE PURPOSE OF THIS MODIFICATION IS TO UPDATE SECTION F.1 & THE PERIOD OF PERFORMANCE FOR LI 0009I THROUGH 0009Q & ADD/EXECUTED CLIN 17.

THIS TASK ORDER ESTABLISHES SERVICES FOR H5 PANDEMIC READINESS FOR ACQUISITION OF MEDICAL COUNTERMEASURES (MCMS) FOR PANDEMIC INFLUENZA AND EMERGING DISEASES PREPAREDNESS AND RESPONSE, UNDER IDIQ 75A50122D00004.

THIS TASK ORDER ESTABLISHES SERVICES FOR H5 PANDEMIC READINESS FOR ACQUISITION OF MEDICAL COUNTERMEASURES (MCMS) FOR PANDEMIC INFLUENZA AND EMERGING DISEASES PREPAREDNESS AND RESPONSE, UNDER IDIQ 75A50122D00004.

THE PURPOSE OF THIS MODIFICATION IS TO REFLECT THE FOLLOWING: 1. EXECUTE FAR 52.217-9 "OPTION TO EXTEND THE TERM OF THE CONTRACT" EXERCISING OPTION PERIOD. OPTION 1'S PERIOD OF PERFORMANCE IS 5/22/2024- 5/21/2025. 2. PROVIDE FUNDING

-2/21/2025. 2. REVISE THE POP OF OPTION PERIOD 1 FROM 5/22/2024 - 5/21/2025 (12-MONTHS) TO 5/22/2024 - 2/21/2025 (9-MONTHS). OPTION PERIOD 1 DECREASED BY $30,270.00 FROM $118,425.00 TO $88,155.00. 3. ADD OPTION PERIOD 4 WITH A POP FROM 2/22/20

THE PURPOSE OF THIS REQUIREMENT IS TO PROVIDE MEDICAL COUNTERMEASURES (MCMS), SUCH AS VACCINES AND ADJUVANTS, FOR PANDEMIC PREPAREDNESS AND RESPONSE OR AS REQUIRED IN RESPONSE TO A HHS DESIGNATED

THE PURPOSE OF THIS REQUIREMENT IS TO PROVIDE MEDICAL COUNTERMEASURES (MCMS), SUCH AS VACCINES AND ADJUVANTS, FOR PANDEMIC PREPAREDNESS AND RESPONSE OR AS REQUIRED IN RESPONSE TO A HHS DESIGNATED

THE PURPOSE OF THIS MOD IS TO AUTHORIZE THE RESAMPLING OF TWO LOTS OF DODS H5N1 A/INDONESIA MONOBULK ANTIGEN FOR STABILITY TESTING IN TASK ORDER 75A50123F61006 CLIN 0017A. THE RESAMPLING OF THE MONOBULK WILL PROVIDE EIGHT ADDITIONAL TIME POINTS (FIVE

THE PURPOSE OF THIS MODIFICATION IS TO EXERCISE OPTION YEAR 8 (0009H).

ASPR-17-04688 -- SEQIRUS -- STORAGE/STABILITY

ASPR-18-00579

THE PURPOSE OF THIS MODIFICATION IS TO TRANSFER MATERIALS FROM TASK ORDER 75A50122F61004 AND TASK ORDER 75A50121F33010 -TO- TASK ORDER 75A50123F61005 FOR STORAGE AND STABILITY FOR CLINS 0007B, 0007C AND 0017B. IN ADDITION, THIS MODIFICATION IS TO

TO DE-OBLIGATION & CLOSEOUT TASK ORDER.

ACQUISITION OF INFLUENZA A/ASTRAKHAN/3212/2020 (H5N8) BULK LOT AND FORMULATE AND FILL ANTIGEN INTO FINAL CONTAINERS.

THE PURPOSE OF THIS MODIFICATION IS TO CO-FORMULATE THE ANTIGEN AND ADJUVANT OF THE REMAINING BATCH THAT IS SCHEDULED TO EXPIRE ON MARCH 06, 2023 THEREFORE; THE FOLLOWING CHANGES/UPDATES WERE MADE: 1. CLIN 0006B1 (FORMULATION AND FILLING: ANTIGEN

THE PURPOSE OF THIS TASK ORDER IS TO PROCURE STORAGE AND STABILITY OF ANTIGEN AND ADJUVANTS FROM PRIOR CONTRACTS FOR DEPARTMENT OF DEFENSE (DOD) UNDER IDIQ CONTRACT 75A50122D00004 DURING BASE PERIOD YEAR 2.

THE PURPOSE OF THIS TASK ORDER IS TO PROCURE SERVICES FOR STORAGE AND STABILITY OF ANTIGENS AND ADJUVANTS FROM PRIOR CONTRACTS FOR DEPARTMENT OF HEALTH AND HUMAN SERVICES UNDER IDIQ CONTRACT 75A50122D00004 DURING BASE PERIOD YEAR 2.

THE PURPOSE OF THIS MODIFICATION IS TO EXERCISE OY7 (0009G)

THE PURPOSE OF THIS TASK ORDER IS TO PROCURE A INFLUENZA A(H2NX) VIRUS VACCINE CANDIDATE(S) AND CONDUCT CLINICAL TRIAL.

THE PURPOSE OF THIS TASK ORDER IS TO PROCURE INFLUENZA A/ASTRAKHAN/3212/2020 (H5N8)-LIKE MASTER AND WORKING SEED LOT FOR THE DEPARTMENT OF HEALTH AND HUMAN SERVICES UNDER IDIQ CONTRACT #75A50122D00004 DURING BASE PERIOD YEAR 1.

THE PURPOSE OF THIS TASK ORDER IS TO PROCURE INFLUENZA A/ASTRAKHAN/3212/2020 (H5N8)-LIKE MASTER AND WORKING SEED LOT FOR DEPARTMENT OF HEALTH AND HUMAN SERVICES UNDER IDIQ CONTRACT #75A50122D00004 DURING BASE PERIOD YEAR 1.